Molecular Mechanism of Enzymatic Chlorite Detoxification: Insights from Structural and Kinetic Studies

[Image: see text] The heme enzyme chlorite dismutase (Cld) catalyzes the degradation of chlorite to chloride and dioxygen. Although structure and steady-state kinetics of Clds have been elucidated, many questions remain (e.g., the mechanism of chlorite cleavage and the pH dependence of the reaction)...

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Publicado en:ACS Catal
Main Authors: Schaffner, Irene, Mlynek, Georg, Flego, Nicola, Pühringer, Dominic, Libiseller-Egger, Julian, Coates, Leighton, Hofbauer, Stefan, Bellei, Marzia, Furtmüller, Paul G., Battistuzzi, Gianantonio, Smulevich, Giulietta, Djinović-Carugo, Kristina, Obinger, Christian
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2017
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5678291/
https://ncbi.nlm.nih.gov/pubmed/29142780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.7b01749
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