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Elevated μs-ms timescale backbone dynamics in the transition state analog form of arginine kinase

Arginine kinase catalyzes reversible phosphoryl transfer between arginine and ATP. Crystal structures of arginine kinase in an open, substrate-free form and closed, transition state analog (TSA) complex indicate that the enzyme undergoes substantial domain and loop rearrangements required for substr...

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Bibliographic Details
Published in:J Struct Biol
Main Authors: Davulcu, Omar, Peng, Yu, Brüschweiler, Rafael, Skalicky, Jack J., Chapman, Michael S.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677571/
https://ncbi.nlm.nih.gov/pubmed/28495594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.05.002
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