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Elevated μs-ms timescale backbone dynamics in the transition state analog form of arginine kinase
Arginine kinase catalyzes reversible phosphoryl transfer between arginine and ATP. Crystal structures of arginine kinase in an open, substrate-free form and closed, transition state analog (TSA) complex indicate that the enzyme undergoes substantial domain and loop rearrangements required for substr...
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| 發表在: | J Struct Biol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5677571/ https://ncbi.nlm.nih.gov/pubmed/28495594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.05.002 |
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