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Elevated μs-ms timescale backbone dynamics in the transition state analog form of arginine kinase
Arginine kinase catalyzes reversible phosphoryl transfer between arginine and ATP. Crystal structures of arginine kinase in an open, substrate-free form and closed, transition state analog (TSA) complex indicate that the enzyme undergoes substantial domain and loop rearrangements required for substr...
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| Publicado no: | J Struct Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5677571/ https://ncbi.nlm.nih.gov/pubmed/28495594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.05.002 |
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