Independent manipulation of histone H3 modifications in individual nucleosomes reveals the contributions of sister histones to transcription

Histone tail modifications can greatly influence chromatin-associated processes. Asymmetrically modified nucleosomes exist in multiple cell types, but whether modifications on both sister histones contribute equally to chromatin dynamics remains elusive. Here, we devised a bivalent nucleosome system...

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Veröffentlicht in:eLife
Hauptverfasser: Zhou, Zhen, Liu, Yu-Ting, Ma, Li, Gong, Ting, Hu, Ya-Nan, Li, Hong-Tao, Cai, Chen, Zhang, Ling-Li, Wei, Gang, Zhou, Jin-Qiu
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Chromosomes and Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5677365/
https://ncbi.nlm.nih.gov/pubmed/29027902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30178
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