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Chemodrug delivery using integrin-targeted PLGA-Chitosan nanoparticle for lung cancer therapy

In this study, we report the efficacy of RGD (arginine-glycine-aspartic acid) peptide-modified polylactic acid-co-glycolic acid (PLGA)-Chitosan nanoparticle (CSNP) for integrin α(v)β(3) receptor targeted paclitaxel (PTX) delivery in lung cancer cells and its impact on normal cells. RGD peptide-modif...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Babu, Anish, Amreddy, Narsireddy, Muralidharan, Ranganayaki, Pathuri, Gopal, Gali, Hariprasad, Chen, Allshine, Zhao, Yan D., Munshi, Anupama, Ramesh, Rajagopal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676784/
https://ncbi.nlm.nih.gov/pubmed/29116098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15012-5
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