Correction of β-thalassemia mutant by base editor in human embryos

β-Thalassemia is a global health issue, caused by mutations in the HBB gene. Among these mutations, HBB −28 (A>G) mutations is one of the three most common mutations in China and Southeast Asia patients with β-thalassemia. Correcting this mutation in human embryos may prevent the disease being pa...

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Vydáno v:Protein Cell
Hlavní autoři: Liang, Puping, Ding, Chenhui, Sun, Hongwei, Xie, Xiaowei, Xu, Yanwen, Zhang, Xiya, Sun, Ying, Xiong, Yuanyan, Ma, Wenbin, Liu, Yongxiang, Wang, Yali, Fang, Jianpei, Liu, Dan, Songyang, Zhou, Zhou, Canquan, Huang, Junjiu
Médium: Artigo
Jazyk:Inglês
Vydáno: Higher Education Press 2017
Témata:
Short Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676594/
https://ncbi.nlm.nih.gov/pubmed/28942539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0475-6
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