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Silymarin Ameliorates Diabetes-Induced Proangiogenic Response in Brain Endothelial Cells through a GSK-3β Inhibition-Induced Reduction of VEGF Release

Diabetes mellitus (DM) is a major risk factor for cardiovascular disease. Additionally, it was found to induce a dysfunctional angiogenic response in the brain that was attributed to oxidative stress. Milk thistle seed extract (silymarin) has potent antioxidant properties, though its potential use i...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Alhusban, Ahmed, Alkhazaleh, Enaam, El-Elimat, Tamam
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5676450/
https://ncbi.nlm.nih.gov/pubmed/29209632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2537216
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