Mesenchymal stem cells ameliorate B-cell-mediated immune responses and increase IL-10-expressing regulatory B cells in an EBI3-dependent manner

Effector B cells are central contributors to the development of autoimmune disease by activating autoreactive T cells, producing pro-inflammatory cytokines and organizing ectopic lymphoid tissue. Conversely, IL-10-producing regulatory B (B(reg)) cells have pivotal roles in maintaining immunological...

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Veröffentlicht in:Cell Mol Immunol
Hauptverfasser: Cho, Kyung-Ah, Lee, Jun-Kyu, Kim, Yu-Hee, Park, Minhwa, Woo, So-Youn, Ryu, Kyung-Ha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675953/
https://ncbi.nlm.nih.gov/pubmed/28042143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2016.59
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