Features of CRISPR-Cas Regulation Key to Highly Efficient and Temporally-Specific crRNA Production

Bacterial immune systems, such as CRISPR-Cas or restriction-modification (R-M) systems, affect bacterial pathogenicity and antibiotic resistance by modulating horizontal gene flow. A model system for CRISPR-Cas regulation, the Type I-E system from Escherichia coli, is silent under standard laborator...

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Foilsithe in:Front Microbiol
Main Authors: Rodic, Andjela, Blagojevic, Bojana, Djordjevic, Magdalena, Severinov, Konstantin, Djordjevic, Marko
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2017
Ábhair:
Microbiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675862/
https://ncbi.nlm.nih.gov/pubmed/29163425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.02139
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