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Opposing roles of rapid dopamine signaling across the rostral-caudal axis of the nucleus accumbens shell in drug-induced negative affect

BACKGROUND: Negative reinforcement theories of drug addiction posit that addicts use drugs to alleviate negative mood states. In a preclinical model developed in our laboratory, rats exhibit negative affect to a normally rewarding taste cue when it predicts impending but delayed cocaine. The emergen...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Hurley, Seth W., West, Elizabeth A., Carelli, Regina M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675798/
https://ncbi.nlm.nih.gov/pubmed/28624112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2017.05.009
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