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A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina

The majority of inherited retinal degenerations converge on the phenotype of photoreceptor cell death. Second- and third-order neurons are spared in these diseases, making it possible to restore retinal light responses using optogenetics. Viral expression of channelrhodopsin in the third-order neuro...

詳細記述

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書誌詳細
出版年:Mol Ther
主要な著者: Chaffiol, Antoine, Caplette, Romain, Jaillard, Céline, Brazhnikova, Elena, Desrosiers, Mélissa, Dubus, Elisabeth, Duhamel, Laëtitia, Macé, Emilie, Marre, Olivier, Benoit, Patrick, Hantraye, Philippe, Bemelmans, Alexis-Pierre, Bamberg, Ernst, Duebel, Jens, Sahel, José-Alain, Picaud, Serge, Dalkara, Deniz
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675708/
https://ncbi.nlm.nih.gov/pubmed/28807567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2017.07.011
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