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Cortactin in cancer cell migration and invasion
Cortactin, a substrate of sarcoma (Src) kinases, is an actin-binding protein that is involved in cytoskeletal regulation, and is frequently overexpressed in cancer cells. Binding to the actin related protein 2/3 (Arp2/3) complex stimulates cortactin activity, which promotes F-actin nucleation and as...
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| Published in: | Oncotarget |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5675706/ https://ncbi.nlm.nih.gov/pubmed/29152154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21088 |
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