The long non-coding RNA PARTICLE is associated with WWOX and the absence of FRA16D breakage in osteosarcoma patients

Breakage of the fragile site FRA16D disrupts the WWOX (WW Domain Containing Oxidoreductase) tumor suppressor gene in osteosarcoma. However, the frequency of breakage is not sufficient to explain the rate of WWOX loss in pathogenesis. The involvement of non-coding RNA transcripts is proposed due to t...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: O'Leary, Valerie Bríd, Maugg, Doris, Smida, Jan, Baumhoer, Daniel, Nathrath, Michaela, Ovsepian, Saak Victor, Atkinson, Michael John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675644/
https://ncbi.nlm.nih.gov/pubmed/29152092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21086
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