A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis

The islets of Langerhans are endocrine organs characteristically dispersed throughout the pancreas. During development, endocrine progenitors delaminate, migrate radially and cluster to form islets. Despite the distinctive distribution of islets, spatially localized signals that control islet morpho...

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Bibliografiske detaljer
Udgivet i:Development
Main Authors: Pauerstein, Philip T., Tellez, Krissie, Willmarth, Kirk B., Park, Keon Min, Hsueh, Brian, Efsun Arda, H., Gu, Xueying, Aghajanian, Haig, Deisseroth, Karl, Epstein, Jonathan A., Kim, Seung K.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675443/
https://ncbi.nlm.nih.gov/pubmed/28893946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.148684
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