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Robust Detection of Genetic Associations in the Presence of Gene-Environment Interaction and Independence

We consider the detection and evaluation of genetic effects in the presence of gene-environment interaction and independence. Whereas ordinary logistic regression cannot exploit the gene-environment independence assumption, we present a novel approach which makes explicit use of this assumption to i...

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Detalhes bibliográficos
Publicado no:Epidemiology
Autor principal: Tchetgen Tchetgen, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675030/
https://ncbi.nlm.nih.gov/pubmed/21228701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/EDE.0b013e318207ffc3
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