Tumor-associated neutrophils induce apoptosis of non-activated CD8 T-cells in a TNFα and NO-dependent mechanism, promoting a tumor-supportive environment

The role of neutrophils in tumor progression has become in recent years a subject of growing interest. Tumor-associated neutrophils (TANs), which constitute an important portion of the tumor microenvironment, promote immunosuppression in advanced tumors by modulating the proliferation, activation an...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Michaeli, Janna, Shaul, Merav E., Mishalian, Inbal, Hovav, Avi-Hai, Levy, Liran, Zolotriov, Lidia, Granot, Zvi, Fridlender, Zvi G.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674962/
https://ncbi.nlm.nih.gov/pubmed/29147615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1356965
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