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Karyopherins regulate nuclear pore complex barrier and transport function
Nucleocytoplasmic transport is sustained by karyopherins (Kaps) and a Ran guanosine triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)–specific cargoes (NLS-cargoes) into the nucleus. However, how nuclear pore complex (NPC) barrier selectivity, Kap traffic, and NLS-cargo r...
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| Veröffentlicht in: | J Cell Biol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5674887/ https://ncbi.nlm.nih.gov/pubmed/28864541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201702092 |
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