Dendritic Cell Amiloride-Sensitive Channels Mediate Sodium-Induced Inflammation and Hypertension

Sodium accumulates in the interstitium and promotes inflammation through poorly defined mechanisms. We describe a pathway by which sodium enters dendritic cells (DCs) through amiloride-sensitive channels including the alpha and gamma subunits of the epithelial sodium channel and the sodium hydrogen...

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Pubblicato in:Cell Rep
Autori principali: Barbaro, Natalia R., Foss, Jason D., Kryshtal, Dmytro O., Tsyba, Nikita, Kumaresan, Shivani, Xiao, Liang, Mernaugh, Raymond L., Itani, Hana A., Loperena, Roxana, Chen, Wei, Dikalov, Sergey, Titze, Jens M., Knollmann, Bjorn C., Harrison, David G., Kirabo, Annet
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674815/
https://ncbi.nlm.nih.gov/pubmed/29069584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.10.002
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