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SIM2l attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma

Despite chemoradiotherapy being one of the most important modalities in advanced cervical cancer, there is a lack of both usable biomarkers to predict treatment outcome and of knowledge about the mechanism of refractoriness to the therapy. Here we identified a transcriptional factor Single-minded ho...

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Foilsithe in:Sci Rep
Main Authors: Nakamura, Kanako, Komatsu, Masayuki, Chiwaki, Fumiko, Takeda, Takashi, Kobayashi, Yusuke, Banno, Kouji, Aoki, Daisuke, Yoshida, Teruhiko, Sasaki, Hiroki
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674005/
https://ncbi.nlm.nih.gov/pubmed/29109451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15261-4
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