SIM2l attenuates resistance to hypoxia and tumor growth by transcriptional suppression of HIF1A in uterine cervical squamous cell carcinoma

Despite chemoradiotherapy being one of the most important modalities in advanced cervical cancer, there is a lack of both usable biomarkers to predict treatment outcome and of knowledge about the mechanism of refractoriness to the therapy. Here we identified a transcriptional factor Single-minded ho...

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Vydáno v:Sci Rep
Hlavní autoři: Nakamura, Kanako, Komatsu, Masayuki, Chiwaki, Fumiko, Takeda, Takashi, Kobayashi, Yusuke, Banno, Kouji, Aoki, Daisuke, Yoshida, Teruhiko, Sasaki, Hiroki
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674005/
https://ncbi.nlm.nih.gov/pubmed/29109451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15261-4
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