Detection of subclonal L1 transductions in colorectal cancer by long-distance inverse-PCR and Nanopore sequencing

Long interspersed nuclear elements-1 (L1s) are a large family of retrotransposons. Retrotransposons are repetitive sequences that are capable of autonomous mobility via a copy-and-paste mechanism. In most copy events, only the L1 sequence is inserted, however, they can also mobilize the flanking non...

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Pubblicato in:Sci Rep
Autori principali: Pradhan, Barun, Cajuso, Tatiana, Katainen, Riku, Sulo, Päivi, Tanskanen, Tomas, Kilpivaara, Outi, Pitkänen, Esa, Aaltonen, Lauri A., Kauppi, Liisa, Palin, Kimmo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673974/
https://ncbi.nlm.nih.gov/pubmed/29109480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15076-3
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