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A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing

Liver chips have been developed to recapitulate in vivo physiological conditions to enhance hepatocyte functions for assessing acute responses to drugs. To develop liver chips that can assess repeated dosing chronic hepatotoxicity, we need to ensure that hepatocyte functions be maintained at constan...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yu, Fang, Deng, Rensheng, Hao Tong, Wen, Huan, Li, Chan Way, Ng, IslamBadhan, Anik, Iliescu, Ciprian, Yu, Hanry
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673965/
https://ncbi.nlm.nih.gov/pubmed/29109520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13848-5
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