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A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing
Liver chips have been developed to recapitulate in vivo physiological conditions to enhance hepatocyte functions for assessing acute responses to drugs. To develop liver chips that can assess repeated dosing chronic hepatotoxicity, we need to ensure that hepatocyte functions be maintained at constan...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673965/ https://ncbi.nlm.nih.gov/pubmed/29109520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13848-5 |
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