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ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair
Global-genome nucleotide excision repair (GG-NER) prevents ultraviolet (UV) light-induced skin cancer by removing mutagenic cyclobutane pyrimidine dimers (CPDs). These lesions are formed abundantly on DNA wrapped around histone octamers in nucleosomes, but a specialized damage sensor known as DDB2 e...
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| Publicado en: | Nat Commun |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673894/ https://ncbi.nlm.nih.gov/pubmed/29109511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01080-8 |
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