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RNA interference-mediated knockdown of SIRT1 and/or SIRT2 in melanoma: Identification of downstream targets by large-scale proteomics analysis

Melanoma is the most notorious and fatal of all skin cancers and the existing treatment options have not been proven to effectively manage this neoplasm, especially the metastatic disease. Sirtuin (SIRT) proteins have been shown to be differentially expressed in melanoma. We have shown that SIRTs 1...

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Publicat a:J Proteomics
Autors principals: Wilking-Busch, Melissa J., Ndiaye, Mary A., Liu, Xiaoqi, Ahmad, Nihal
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673532/
https://ncbi.nlm.nih.gov/pubmed/28882678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2017.09.002
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