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Visualization of phage DNA degradation by a type I CRISPR-Cas system at the single-cell level

BACKGROUND: The CRISPR-Cas system is a widespread prokaryotic defense system which targets and cleaves invasive nucleic acids, such as plasmids or viruses. So far, a great number of studies have focused on the components and mechanisms of this system, however, a direct visualization of CRISPR-Cas de...

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Bibliografiske detaljer
Udgivet i:Quant Biol
Main Authors: Guan, Jingwen, Shi, Xu, Burgos, Roberto, Zeng, Lanying
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673134/
https://ncbi.nlm.nih.gov/pubmed/29119038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40484-017-0099-0
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