Serum Vascular Endothelial Growth Factor and COX-2/5-LOX Inhibition in Advanced Non-small Cell Lung Cancer: Cancer and Leukemia Group B 150304

INTRODUCTION: Eicosanoids, including PGE-2 and 5-HETE, can increase levels of plasma vascular endothelial growth factor (VEGF). Overexpression of COX-2 or 5-LOX increases levels of PGE-2 and 5-HETE, respectively. Elevated levels of VEGF are common in patients with non-small cell lung cancer (NSCLC)....

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Pubblicato in:J Thorac Oncol
Autori principali: Edelman, Martin J., Hodgson, Lydia, Wang, Xiaofei, Christenson, Robert, Jewell, Scott, Vokes, Everett, Kratzke, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673085/
https://ncbi.nlm.nih.gov/pubmed/21964530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e31822a7383
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