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Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells
Interleukin-15 (IL-15) is essential for the development and maintenance of natural killer (NK) cells. IL-15 activates STAT5 proteins, which can form dimers or tetramers. We previously found that NK cell numbers are decreased in Stat5a−Stat5b tetramer-deficient double knockin (DKI) mice, but the mech...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673064/ https://ncbi.nlm.nih.gov/pubmed/29105654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01477-5 |
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