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Salicylic acid metabolites and derivatives inhibit CDK activity: Novel insights into aspirin's chemopreventive effects against colorectal cancer

Aspirin's potential as a drug continues to be evaluated for the prevention of colorectal cancer (CRC). Although multiple targets for aspirin and its metabolite, salicylic acid, have been identified, no unifying mechanism has been proposed to clearly explain its chemopreventive effects. Our goal...

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Bibliografiske detaljer
Udgivet i:Int J Oncol
Main Authors: Dachineni, Rakesh, Kumar, D. Ramesh, Callegari, Eduardo, Kesharwani, Siddharth S., Sankaranarayanan, Ranjini, Seefeldt, Teresa, Tummala, Hemachand, Bhat, G. Jayarama
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673027/
https://ncbi.nlm.nih.gov/pubmed/29075787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2017.4167
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