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Allopurinol in combination with thiopurine induces mucosal healing and improves clinical and metabolic outcomes in IBD
BACKGROUND: Thiopurines, azathioprine (AZA) and 6-mercaptopurine (6-MP) are common maintenance medications for inflammatory bowel disease (IBD). Excessive methylation via thiopurine methyltransferase (TPMT) frequently causes therapeutic failure. Allopurinol reduces excessive 6-methyl-mercaptopurine...
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| Publicat a: | Therap Adv Gastroenterol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
SAGE Publications
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5673019/ https://ncbi.nlm.nih.gov/pubmed/29147133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X17733657 |
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