Separase is a marker for prognosis and mitotic activity in breast cancer

BACKGROUND: Cancer cell proliferation is a critical feature in classifying and predicting the outcome of breast carcinoma. Separase has a central role in cell cycle progression in unleashing sister-chromatids at anaphase onset. Abnormally functioning separase is known to lead to chromosomal instabil...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Autores principales: Gurvits, Natalia, Löyttyniemi, Eliisa, Nykänen, Marjukka, Kuopio, Teijo, Kronqvist, Pauliina, Talvinen, Kati
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672940/
https://ncbi.nlm.nih.gov/pubmed/28859055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.301
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