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RNA helicase DHX15 acts as a tumour suppressor in glioma

BACKGROUND: Glioblastoma is the most common form of malignant brain cancer and has a poor prognosis in adults. We identified Dhx15 as a candidate tumour suppressor gene in glioma by transposon-based mutagenesis. Dhx15 is an adenosine triphosphate (ATP)-dependent RNA helicase belonging to the DEAH-bo...

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Podrobná bibliografie
Vydáno v:Br J Cancer
Hlavní autoři: Ito, Shingo, Koso, Hideto, Sakamoto, Kazuhiro, Watanabe, Sumiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672939/
https://ncbi.nlm.nih.gov/pubmed/28829764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.273
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