Ligand-dependent Hedgehog pathway activation in Rhabdomyosarcoma: the oncogenic role of the ligands

BACKGROUND: Rhabdomyosarcoma (RMS) is the most common type of soft tissue sarcoma in children. The Hedgehog (HH) pathway is known to develop an oncogenic role in RMS. However, the molecular mechanism that drives activation of the pathway in RMS is not well understood. METHODS: The expression of HH l...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Almazán-Moga, A, Zarzosa, P, Molist, C, Velasco, P, Pyczek, J, Simon-Keller, K, Giralt, I, Vidal, I, Navarro, N, Segura, M F, Soriano, A, Navarro, S, Tirado, O M, Ferreres, J C, Santamaria, A, Rota, R, Hahn, H, Sánchez de Toledo, J, Roma, J, Gallego, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672936/
https://ncbi.nlm.nih.gov/pubmed/28881358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.305
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados