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Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Quantification

Quantitative matrix-assisted laser desorption/ionization time-of-flight (MALDI TOF) approaches have historically suffered from poor accuracy and precision mainly due to the nonuniform distribution of matrix and analyte across the target surface, matrix interferences, and ionization suppression. Tand...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Prentice, Boone M., Chumbley, Chad W., Hachey, Brian C., Norris, Jeremy L., Caprioli, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672909/
https://ncbi.nlm.nih.gov/pubmed/27573922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b02821
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