Cytomegalovirus vector expressing RAE-1γ induces enhanced anti-tumor capacity of murine CD8+ T cells

Designing of CD8 T cell vaccines which would provide protection against tumors is still considered a great challenge in immunotherapy. Here we show a robust potential of a cytomegalovirus (CMV) vector expressing the NKG2D ligand RAE-1γ as CD8 T cell-based vaccine against malignant tumors. Immunizati...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Tršan, Tihana, Vuković, Kristina, Filipović, Petra, Lesac Brizić, Ana, Lemmermann, Niels A. W., Schober, Kilian, Busch, Dirk H., Britt, William J., Messerle, Martin, Krmpotić, Astrid, Jonjić, Stipan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672794/
https://ncbi.nlm.nih.gov/pubmed/28612942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201746964
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