CD40L Expression Allows CD8(+) T Cells to Promote Their Own Expansion and Differentiation through Dendritic Cells

CD8(+) T cells play an important role in providing protective immunity against a wide range of pathogens, and a number of different factors control their activation. Although CD40L-mediated CD40 licensing of dendritic cells (DCs) by CD4(+) T cells is known to be necessary for the generation of a rob...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Tay, Neil Q., Lee, Debbie C. P., Chua, Yen Leong, Prabhu, Nayana, Gascoigne, Nicholas R. J., Kemeny, David M.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672143/
https://ncbi.nlm.nih.gov/pubmed/29163545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01484
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