The Molecular Chaperone Artemin Efficiently Blocks Fibrillization of TAU Protein In Vitro

OBJECTIVE: Aggregation of the TAU proteins in the form of neurofibrillary tangles (NFTs) in the brain is a common risk factor in tauopathies including Alzheimer’s disease (AD). Several strategies have been implemented to target NFTs, among which chaperones, which facilitate the proper folding of pro...

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Foilsithe in:Cell J
Main Authors: Khosravi, Zahra, Nasiri Khalili, Mohammad Ali, Moradi, Sharif, Hassan Sajedi, Reza, Zeinoddini, Mehdi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Royan Institute 2018
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Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672095/
https://ncbi.nlm.nih.gov/pubmed/29105391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2018.4510
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