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Apolipoprotein L1 confers pH-switchable ion permeability to phospholipid vesicles

Apolipoprotein L1 (ApoL1) is a human serum protein conferring resistance to African trypanosomes, and certain ApoL1 variants increase susceptibility to some progressive kidney diseases. ApoL1 has been hypothesized to function like a pore-forming colicin and has been reported to have permeability eff...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Bruno, Jonathan, Pozzi, Nicola, Oliva, Jonathan, Edwards, John C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672055/
https://ncbi.nlm.nih.gov/pubmed/28918394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813444
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