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Neutrophil microparticle production and inflammasome activation by hyperglycemia due to cytoskeletal instability
Microparticles are lipid bilayer–enclosed vesicles produced by cells under oxidative stress. MP production is elevated in patients with diabetes, but the underlying cellular mechanisms are poorly understood. We hypothesized that raising glucose above the physiological level of 5.5 mm would stimulate...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5672053/ https://ncbi.nlm.nih.gov/pubmed/28972154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802629 |
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