Phosphoproteomics reveals that glycogen synthase kinase-3 phosphorylates multiple splicing factors and is associated with alternative splicing

Glycogen synthase kinase-3 (GSK-3) is a constitutively active, ubiquitously expressed protein kinase that regulates multiple signaling pathways. In vitro kinase assays and genetic and pharmacological manipulations of GSK-3 have identified more than 100 putative GSK-3 substrates in diverse cell types...

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Publicat a:J Biol Chem
Autors principals: Shinde, Mansi Y., Sidoli, Simone, Kulej, Katarzyna, Mallory, Michael J., Radens, Caleb M., Reicherter, Amanda L., Myers, Rebecca L., Barash, Yoseph, Lynch, Kristen W., Garcia, Benjamin A., Klein, Peter S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672046/
https://ncbi.nlm.nih.gov/pubmed/28916722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.813527
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