Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker

BACKGROUND: Preeclampsia is a complex and common human-specific pregnancy syndrome associated with placental pathology. The human specificity provides both intellectual and methodological challenges, lacking a robust model system. Given the role of imprinted genes in human placentation and the vulne...

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Vydáno v:Circulation
Hlavní autoři: Zadora, Julianna, Singh, Manvendra, Herse, Florian, Przybyl, Lukasz, Haase, Nadine, Golic, Michaela, Yung, Hong Wa, Huppertz, Berthold, Cartwright, Judith E., Whitley, Guy, Johnsen, Guro M., Levi, Giovanni, Isbruch, Annette, Schulz, Herbert, Luft, Friedrich C., Müller, Dominik N., Staff, Anne Cathrine, Hurst, Laurence D., Dechend, Ralf, Izsvák, Zsuzsanna
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2017
Témata:
Original Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671803/
https://ncbi.nlm.nih.gov/pubmed/28904069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.028110
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