Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker

BACKGROUND: Preeclampsia is a complex and common human-specific pregnancy syndrome associated with placental pathology. The human specificity provides both intellectual and methodological challenges, lacking a robust model system. Given the role of imprinted genes in human placentation and the vulne...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Zadora, Julianna, Singh, Manvendra, Herse, Florian, Przybyl, Lukasz, Haase, Nadine, Golic, Michaela, Yung, Hong Wa, Huppertz, Berthold, Cartwright, Judith E., Whitley, Guy, Johnsen, Guro M., Levi, Giovanni, Isbruch, Annette, Schulz, Herbert, Luft, Friedrich C., Müller, Dominik N., Staff, Anne Cathrine, Hurst, Laurence D., Dechend, Ralf, Izsvák, Zsuzsanna
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2017
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671803/
https://ncbi.nlm.nih.gov/pubmed/28904069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.028110
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