Leptin Induces Sca-1(+) Progenitor Cell Migration Enhancing Neointimal Lesions in Vessel-Injury Mouse Models

OBJECTIVE—: Leptin is an adipokine initially thought to be a metabolic factor. Recent publications have shown its roles in inflammation and vascular disease, to which Sca-1(+) vascular progenitor cells within the vessel wall may contribute. We sought to elucidate the effects of leptin on Sca-1(+) pr...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Xie, Yao, Potter, Claire M.F., Le Bras, Alexandra, Nowak, Witold N., Gu, Wenduo, Bhaloo, Shirin Issa, Zhang, Zhongyi, Hu, Yanhua, Zhang, Li, Xu, Qingbo
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2017
Témata:
Basic Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671780/
https://ncbi.nlm.nih.gov/pubmed/28935755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.309852
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