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Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice
To evaluate RNA oxidation in the early stage of diabetic nephropathy, we applied an accurate method based on isotope dilution high-performance liquid chromatography-triple quadruple mass spectrometry to analyze the oxidatively generated guanine nucleosides in renal tissue and urine from db/db mice o...
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Published in: | Oxid Med Cell Longev |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
Hindawi
2017
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5671745/ https://ncbi.nlm.nih.gov/pubmed/29201270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2353729 |
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