Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice

To evaluate RNA oxidation in the early stage of diabetic nephropathy, we applied an accurate method based on isotope dilution high-performance liquid chromatography-triple quadruple mass spectrometry to analyze the oxidatively generated guanine nucleosides in renal tissue and urine from db/db mice o...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Wang, Wan-Xia, Luo, Shun-Bin, Jiang, Ping, Xia, Meng-Ming, Hei, Ai-lian, Mao, Yong-Hui, Li, Chuan-Bao, Hu, Guo-Xin, Cai, Jian-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671745/
https://ncbi.nlm.nih.gov/pubmed/29201270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/2353729
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