Generation of an Attenuated Tiantan Vaccinia Virus Strain by Deletion of Multiple Genes

An attenuated vaccinia virus-MVTT(EAB)-was constructed by deletion of non-essential gene segments related to the immunomodulatory and virulence functions of the vaccinia virus Tiantan strain (VVTT). The shuttle plasmids pTC-EGFP, pTE-EGFP, pTA35-EGFP, pTB-EGFP, and pTA66-EGFP were constructed and co...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Li, Yiquan, Zhu, Yilong, Chen, Shuang, Li, Wenjie, Yin, Xunzhe, Li, Shanzhi, Xiao, Pengpeng, Han, Jicheng, Li, Xiao, Sun, Lili, Jin, Ningyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671601/
https://ncbi.nlm.nih.gov/pubmed/29164070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00462
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