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The effect of long-term bisphosphonate therapy on trabecular bone strength and microcrack density

OBJECTIVES: Bisphosphonates (BP) are the first-line treatment for preventing fragility fractures. However, concern regarding their efficacy is growing because bisphosphonate is associated with over-suppression of remodelling and accumulation of microcracks. While dual-energy X-ray absorptiometry (DX...

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Detalhes bibliográficos
Publicado no:Bone Joint Res
Main Authors: Jin, A., Cobb, J., Hansen, U., Bhattacharya, R., Reinhard, C., Vo, N., Atwood, R., Li, J., Karunaratne, A., Wiles, C., Abel, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670367/
https://ncbi.nlm.nih.gov/pubmed/29066534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.610.BJR-2016-0321.R1
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