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piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm

Piwi-interacting RNAs (piRNAs) and PIWI proteins play a crucial role in germ cells by repressing transposable elements and regulating gene expression. In Drosophila, maternal piRNAs are loaded into the embryo mostly bound to the PIWI protein Aubergine (Aub). Aub targets maternal mRNAs through incomp...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Dufourt, Jérémy, Bontonou, Gwénaëlle, Chartier, Aymeric, Jahan, Camille, Meunier, Anne-Cécile, Pierson, Stéphanie, Harrison, Paul F., Papin, Catherine, Beilharz, Traude H., Simonelig, Martine
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670238/
https://ncbi.nlm.nih.gov/pubmed/29101389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01431-5
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