Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917

Administration of the probiotic Escherichia coli strain Nissle 1917 (EcN) decreases visceral pain associated with irritable bowel syndrome. Mutation of clbA, a gene involved in the biosynthesis of secondary metabolites, including colibactin, was previously shown to abrogate EcN probiotic activity. H...

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Publicat a:Nat Commun
Autors principals: Pérez-Berezo, Teresa, Pujo, Julien, Martin, Patricia, Le Faouder, Pauline, Galano, Jean-Marie, Guy, Alexandre, Knauf, Claude, Tabet, Jean Claude, Tronnet, Sophie, Barreau, Frederick, Heuillet, Maud, Dietrich, Gilles, Bertrand-Michel, Justine, Durand, Thierry, Oswald, Eric, Cenac, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5670229/
https://ncbi.nlm.nih.gov/pubmed/29101366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01403-9
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