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Identification of a peptide-peptide binding motif in the coating of nab-paclitaxel nanoparticles with clinical antibodies: bevacizumab, rituximab, and trastuzumab
Antibody directed chemotherapy (ADC) takes advantage of the selectivity of the monoclonal antibody to increase the efficacy of the chemotherapeutic agent, while reducing toxicity. Previously we described three nab-paclitaxel (Abraxane) nanoparticles coated with commercial monoclonal antibodies. Iden...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Sci Rep |
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Prif Awduron: | , , , , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Nature Publishing Group UK
2017
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5670201/ https://ncbi.nlm.nih.gov/pubmed/29101359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15251-6 |
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