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Antibody-targeted paclitaxel loaded nanoparticles for the treatment of CD20(+) B-cell lymphoma
We developed a nano-antibody targeted chemotherapy (nATC) delivery strategy in which tumor specific and clinically relevant antibodies (rituximab, anti-CD20) are non-covalently bound to the albumin scaffold of nab-paclitaxel (ABX). We define the nanoparticle formed when the 2 drugs are bound (AR160)...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5381215/ https://ncbi.nlm.nih.gov/pubmed/28378801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45682 |
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