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Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure

BACKGROUND: Skeletal muscle wasting is often observed in heart failure (HF). The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis is impaired in HF. In this study, we evaluated the effects of GH on soleus muscle and cardiac remodeling in rats with aortic stenosis (AS)-induced HF. METHOD...

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Pubblicato in:Oncotarget
Autori principali: Lima, Aline R.R., Pagan, Luana U., Damatto, Ricardo L., Cezar, Marcelo D.M., Bonomo, Camila, Gomes, Mariana J., Martinez, Paula F., Guizoni, Daniele M., Campos, Dijon H.S., Damatto, Felipe C., Okoshi, Katashi, Okoshi, Marina P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669945/
https://ncbi.nlm.nih.gov/pubmed/29137319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20583
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