Effects of growth hormone on cardiac remodeling and soleus muscle in rats with aortic stenosis-induced heart failure

BACKGROUND: Skeletal muscle wasting is often observed in heart failure (HF). The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis is impaired in HF. In this study, we evaluated the effects of GH on soleus muscle and cardiac remodeling in rats with aortic stenosis (AS)-induced HF. METHOD...

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Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Lima, Aline R.R., Pagan, Luana U., Damatto, Ricardo L., Cezar, Marcelo D.M., Bonomo, Camila, Gomes, Mariana J., Martinez, Paula F., Guizoni, Daniele M., Campos, Dijon H.S., Damatto, Felipe C., Okoshi, Katashi, Okoshi, Marina P.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669945/
https://ncbi.nlm.nih.gov/pubmed/29137319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20583
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